Archive for the ‘Omega-3 Fats’ Category

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Omega-3 Fats Help Prevent Nerve Damage from Injury and Sciatica

June 19, 2012
Fats From Fish Oil Lower Inflammation to Prevent Nerve Damage

Fats From Fish Oil Lower Inflammation to Prevent Nerve Damage

People that have suffered a traumatic injury face an uphill battle as they attempt to regain their health and fight the risk of depression as a long term consequence of the event. British researchers from Queen Mary at the University of London have published the result of a study in the Journal of Neuroscience that explains how omega-3 fatty acids play a significant role in preventing and protecting nerves from injury.

The research focused on peripheral nerve cells which transmit signals between the brain and the spinal cord to the rest of the body. Omega-3 fats from food sources including sardines, salmon, walnuts and flaxseeds provide for decreased cell death from injury and may offer significant protection against future damage.

Omega-3 Fats Help Prevent Nerve Damage and Assist the Repair Process

Omega-3 Fats Help Nerve Regeneration and Development

Omega-3 Fats Help Nerve Regeneration and Development

Current research indicates that our nerves do have a limited capacity to regenerate, but recovery is severely limited depending on the extent of the injury. Omega-3 fatty acids are essential for the body’s normal growth and development and have been well researched for their health benefits, largely focused on brain and heart health. The body is unable to manufacture its own Omega-3 fat supply, so it is necessary to obtain sufficient intake from foods such as oily fish, nuts and seeds or through supplementation.

Researchers studied the effect of Omega-3 fats on isolated mice nerve cells, known to parallel human nerve responses. They simulated nerve damage caused from an accident or injury by either stretching the cells or starving them of oxygen. Both types of damage can kill a significant portion of nerve cells, but enrichment with omega-3 fatty acids in cells gave them significant protection and decreased cell death.

EPA and DHA Fats Lower Sciatic Nerve Injury Damage and Prevent Muscle Wasting

Fish Oil Fats Shown Beneficial to Prevent Pain From Sciatica

Fish Oil Fats Shown Beneficial to Prevent Pain From Sciatica

The study also examined sciatic nerve damage in the mice. They found that a high level of omega-3 fatty acids helped mice to recover from sciatic nerve injury more quickly and more fully, and that their muscles were less likely to waste following nerve damage. The team leader, Dr. Adina Michael-Titus, Professor of Neuroscience concluded “Our previous research has shown that these fatty acids could have beneficial effects in a number of neurological conditions. This new study suggests that they could also have a role in treating peripheral nerve injuries.”

The findings from this research should come as no surprise to integrative health followers. The Omega-3 fats EPA and DHA are essential building blocks to all cellular structures in the body and are particularly dominant in the brain and nervous system. A healthy supply of Omega-3 fatty acids allows for natural cell repair and the effective chemical and electrical communications that are important to optimal nerve function. Consuming fatty fish three to four times a week or supplementing with molecularly distilled fish oil (1 to 2.4 grams total EPA/DHA) supports the nervous system and regeneration process after injury.

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Study Shows Omega-3 Fats Could Help Prevent Leukemia

May 31, 2012
Omega-3 Fish Oil Compound Targets Leukemia Cells

Omega-3 Fish Oil Compound Targets Leukemia Cells

Scientists from the medical sciences division at Penn State University have discovered that a compound in fish oil appears to target leukemia stem cells and could lead to a cure for the disease. The compound is a natural extract from EPA, the Omega-3 fat component found most commonly in fish and fish oil supplements. Known as delta-12-protaglandin J3, or D12-PGJ3, the molecule is shown to target and kill the stem cells of chronic myelogenous leukemia, a common form of the disease.

Extensive research from past studies has shown that Omega-3 fats are critical to cardiovascular and brain health. This new evidence supports the regular intake of EPA omega-3 fats to selectively kill leukemia-causing stem cells that could prevent and possibly even provide a cure for this devastating disease.

Omega-3 Fat Compound Shown to Kill Stem Cells Necessary for Leukemia Progression

Fish Oil Causes Leukemia Stem Cells to Self Destruct

Fish Oil Causes Leukemia Stem Cells to Self Destruct

The research, currently being conducted on mice that exhibit metabolic characteristics similar to humans, shows that some metabolites of Omega-3 have the ability to selectively kill the leukemia-causing stem cells. Scientists determined that D12-PGJ3 kills cancer-causing stem cells in the mice’s spleen and bone marrow. Specifically, it activates a gene known as p53 in the leukemia stem cell that programs the cells own death in a process called apoptosis.

The p53 gene is a well known “tumor suppressor gene that regulates the response to DNA damage and maintains genomic stability”, noted lead study author Dr. Sandeep Prabhu. The D12-PDJ3 compound kills the leukemic stem cells (leukemia is a cancer of the white blood cells), an important step to prevent the development and division of white blood cells that can be used to propagate new cancerous tissue.

Long-Chain Omega Fats Help Regenerate White Blood Cells to Prevent Leukemia

Omega-3 Fat Component Enables White Blood Cell Regeneration

Omega-3 Fat Component Enables White Blood Cell Regeneration

Current drug therapies are ineffective as they only attempt to keep the number of leukemia cells low, and carry many dangerous and sometimes fatal side effects. Drug therapy for leukemia patients fails to completely cure the disease because they do not target the source of new leukemia stem cells. Current treatments are unable to kill the leukemia stem cells and fall short of providing an effective cure for the disease.

The Omega-3 EPA fat compound, D12-PDJ3 targets regeneration of white blood stem cells, an essential step necessary to cure leukemia. The authors noted there were no side effects from administering the natural fat compound. Researchers from Penn State indicated that the compound would shortly move to human trials, with similar results anticipated. Long chain omega fats have been documented to promote human health and prevent chronic illnesses ranging from heart disease and dementia to metabolic syndrome and stroke. EPA fat compounds (500 mg per day) may help prevent and treat leukemia and other cancer lines dependent on stem cells to replicate and metastasize.

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Omega-3 Fats Improve Insulin Resistance and Lower Heart Disease Risk

February 27, 2012
Fish Oil Fats Improve Blood Lipids to Lower Heart Disease Risks

Fish Oil Fats Improve Blood Lipids to Lower Heart Disease Risks

Compelling evidence now exists to demonstrate that heart disease is largely caused by the proliferation of increased levels of small, dense LDL cholesterol particles that have become oxidized in the blood and abnormalities relating to insulin resistance. Both factors combine to deal a potentially deadly punch to the vascular system, leading to metabolic stress, diabetes and increased risk for a heart attack.

Published studies appearing in the journals Nutrition Review and Biological Psychology detail the impact of nutritional intervention with the long-chain omega-3 fats EPA and DHA to improve insulin signaling and lower heart disease risk. A balanced diet including fatty fish, nuts, seeds and olive oil or fish oil supplementation are shown to significantly improve biological markers associated with diabetes and cardiovascular pathogenesis.

Omega-3 Fats Lower Risk for Heart Disease in Women by 38 Percent

Fish Oil is Shown to Lower Inflammatory Factors That Promote Heart Disease

Fish Oil is Shown to Lower Inflammatory Factors That Promote Heart Disease

Many people discount the effect of mental stress on physical health and cardiovascular disease in particular. Overt demands on the nervous system that result from unresolved stress result in excessive demands on the circulatory system, reduced blood flow to cells and increased levels of damaging inflammation. Combined with a diet favoring poor balance of omega-6 to omega-3 fatty acids, the stage is set for a dangerous deterioration of the cardiovascular system.

Researchers examined 3277 Danish men and women over a period of 23 years to determine the effect of long-chain omega-3 fats on cardiac health. Scientists found that 471 cases of ischemic heart disease (IHD) occurred during the study period. A detailed analysis of the results showed that those participants with the highest intake of EPA and DHA omega-3 fats (1.4 total grams of EPA/DHA per day) experienced the highest risk reduction for IHD. The study authors noted that omega-3 fat intake “was especially clear for women, who had a statistically significant 38 percent risk reduction for heart disease. Men also showed a benefiting trend of 26 percent risk reduction.”

Omega-3 Fat Supplementation Regulates Insulin Function to Lower Inflammatory Disease Risks

Omega-3 Fats Improve Insulin Resistance to Assist Weight Loss

Omega-3 Fats Improve Insulin Resistance to Assist Weight Loss

Further evidence demonstrating the importance of omega-3 fats for optimal human health is published in the journal Nutrition Review. Adiponectin is a potent hormone secreted by white adipose tissue that regulates insulin function and reduces inflammation in your circulatory system. As central abdominal fat increases, adiponectin levels go down, increasing the risk for obesity, diabetes and heart disease. Researchers found that omega-3 fats from diet or supplementation, combined with dietary fiber and exercise increased adiponectin levels up to 60%, dramatically lowering the risk from inflammatory disease and metabolic syndrome.

An extensive body of research continues to mount showing the importance of omega-3 fats as a cornerstone for disease prevention and ideal health. Stress is a part of everyday life that directly impacts disease development and progression on the cellular level. Research confirms that a healthy diet favoring omega-3 fat sources or distilled fish oil supplements (1.2 to 1.4 grams EPA/DHA per day) can negate the effect of stressors that cause inflammation, metabolic dysfunction and cardiovascular disease.

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Omega-3 Fat Ratio and B Vitamins Slow Alzheimer’s Disease

February 20, 2012
Alzheimer's Disease is Largely Precipitated by Poor Nutritional Factors

Alzheimer's Disease is Largely Precipitated by Poor Nutritional Factors

Proper nutritional status attained by consuming a healthy diet teaming with natural vitamins and minerals along with optimization of omega fat lipid ratios can help to prevent cognitive decline associated with Alzheimer’s disease (AD) pathology. Researchers studying the effects of nutrition at Oxford University in England found that daily supplementation with folic acid and vitamins B6 and B12 lowered levels of homocysteine, a known risk factor leading to decline in cognition and memory.

Further evidence published in the journal Molecular Nutrition & Food Research explains that a disproportionate ratio of omega-6 to omega-3 fatty acids plays a crucial role in the development of AD in later life. Cellular nutritional saturation from diet and appropriate supplementation with B vitamins and omega-3 fats may provide the cornerstone to prevent this most feared memory-robbing disease.

B Vitamin Supplementation Shown to Lower Homocysteine by 30% and Slow Brain Atrophy

Study Finds B Vitamins Lowers Homocysteine to Reduce Alzheimer's Risk

Study Finds B Vitamins Lowers Homocysteine to Reduce Alzheimer's Risk

Reporting in the International Journal of Geriatric Psychiatry, scientists examined the proposed link between elevated homocysteine levels and cognitive decline. Homocysteine has already been shown to dramatically increase the risk of heart disease and heart attack in prior studies. Researchers examined 266 people over the age of 70 with established mild cognitive impairment, and broke them into two groups. One group was supplemented with folic acid, vitamin B6 and B12, vitamin cofactors that lower homocysteine levels, while the second group received a placebo.

Brain wasting or atrophy is a common sign of cognitive impairment and is closely associated with Alzheimer’s dementia. The rate of brain atrophy is increased by higher concentrations of homocysteine in the blood and brain tissue. Researchers examining the results of this study found that the group supplemented with B vitamins for a period of two years experienced a 30% reduction in homocysteine levels. They found dramatic improvements in mental tests including global cognition and episodic memory (69% improvement in word recall memory) compared to the control group.

Omega-6 to Omega-3 Fat Ratio in Diet Creates an Imbalance in the Brain

Improper Omega Fat Ratio in Diet Slows Alzheimer's Disease Progression

Improper Omega Fat Ratio in Diet Slows Alzheimer's Disease Progression

The standard American diet (SAD) includes large quantities of oxidized omega-6 fats from fried and processed foods when compared to omega-3 fat consumption (from fish, nuts and seeds). The ratio of omega-6 to omega-3 fatty acids ranges from 20:1 to as high as 50:1 (ideal range is no more than 4:1), creating a perpetual degree of inflammation throughout the body. Researchers have determined that this imbalance creates a disturbance in brain chemistry affecting neurotransmitter balance and electrical firing in the brain that sets the stage for amyloid tangles and cognitive decline.

Reestablishing omega fat homeostasis by balancing toward a 1:1 intake ratio and correcting B vitamin nutritional deficiencies provide deep insight toward understanding and controlling risk factors for the development of many forms of dementia including Alzheimer’s disease. Most middle aged adults will want to include a high potency B vitamin supplement (preferably formulated from natural food sources) and include omega-3 fats from diet or fish oil consumption to lower dementia risk factors.

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Omega-3 Fats Shown to Improve Arthritis Symptoms

February 16, 2012
Humans Have Evolved to Control Joint Inflammation with Omega-3 Fats

Humans Have Evolved to Control Joint Inflammation with Omega-3 Fats

Humans have been consuming omega-3 fats from natural fish, nut and seed sources for countless generations. Our core genetic structure depends on a regular supply of the long chain omega-3 fats EPA and DHA to form cell wall structures and perform millions of metabolic functions that we normally associate with vibrant health.

Imbalance of omega-3 to omega-6 fats cause a surge in inflammatory cytokines that can lead to the painful and debilitating condition known as osteoarthritis. New research published in the journal Osteoarthritis and Cartilage has shown for the first time that omega-3 fats supplied by fish oil could “substantially and significantly” reduce the signs and symptoms of osteoarthritis as we age.

Omega-3 Fat Supplementation Slashes Osteoarthritis Disease Progression by Half

Omega-3 Fat Supplementation Slows Osteoarthritis Progression by 50%

Omega-3 Fat Supplementation Slows Osteoarthritis Progression by 50%

Researchers from the University of Bristol in England tested the effect of omega-3 fats on a breed of guinea pigs that are genetically predisposed to develop arthritis. Guinea pigs were chosen for this study as they develop osteoarthritis in a similar manner to humans. Anecdotal reports over the years provide support for the beneficial effect of fish consumption on joint health. Dr. John Tarlton from the Matrix Biology Research Group and his team set out to confirm the impact of omega-3 fatty acids, either sourced from fish oil or flax oil, to prevent or slow down the progression of osteoarthritis.

The team fed one group of guinea pigs a diet including full-spectrum omega-3 fats (EPA and DHA) and compared the results to a second control group of non-supplemented animals. Typical degradation of collagen in cartilage and the loss of molecules that give it shock-absorbing properties were both reduced in the omega-3 supplemented group. Researchers noted that omega-3 fats reduced disease by 50 per cent compared to the control group.

Omega-3 Fats Found More Effective Treating Arthritis than Dangerous Medications

Natural Omega-3 Fats are More Effective Treating Arthritis Compared to Medications

Natural Omega-3 Fats are More Effective Treating Arthritis Compared to Medications

Upon examination of the results, Dr. Tarlton explained “there was strong evidence that omega-3 influences the biochemistry of the disease, and therefore not only helps prevent disease, but also slows its progression, potentially controlling established osteoarthritis.” This is a critical finding, as most people suffering from arthritis are prescribed a plethora of ineffective pain medications that dramatically increase the risk of developing cardiovascular disease or suffering a heart attack.

At the present time there is no known cure or effective treatment from those experiencing the debilitating effects of osteoarthritis, and omega fat imbalance from a poor diet causes excessive joint inflammation and needless suffering. Researchers performing this study concluded “Most diets in the developed world are lacking in omega-3, with modern diets having up to 30 times too much omega-6 and too little omega-3. Taking omega-3 will help redress this imbalance and may positively contribute to a range of other health problems such as heart disease.” Most health-minded individuals will want to supplement with a molecularly distilled form of fish oil (minimum 1200 mg EPA/DHA content) each day to combat inflammation and osteoarthritis.

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Omega-3 Fatty Acids Lower Mortality Risk Up to Eighty Percent

December 19, 2011
Omega-3 Fats Shown to Extend Natural Lifespan up to 80%

Omega-3 Fats Shown to Extend Natural Lifespan up to 80%

Many people make the potentially fatal presumption that aging, chronic diseases and premature aging are natural events that come with advancing years. A plethora of current research studies confirm that nothing could be farther from the truth. In addition to super-nutrients such as resveratrol, curcumin and vitamin D optimization, researchers publishing in the American Journal of Clinical Nutrition and Clinical Cardiology provide documented evidence that beneficial Omega-3 fatty acids from dietary sources and supplementation slash the overall risk of an early death.

The long-chain fats DHA and EPA elicit a profound effect on the heart and brain to ameliorate chronic diseases that bring an early demise to millions of unsuspecting individuals each year. Health-minded individuals today are used to hearing about the myriad of benefits associated with eating fish and supplementing with Omega-3 fats.

Omega-3 Fat Supplementation Slashes Risk of All-Cause Mortality in Half

Heart Attack Risk Lowered in Those With Prior Heart Disease by 85%

Heart Attack Risk Lowered in Those With Prior Heart Disease by 85%

A wealth of peer-reviewed studies provide solid evidence that the DHA and EPA fatty acids help to prevent heart disease and sudden death from a heart attack, lower depression incidence and reduce stroke and dementia risks as well. New research shows that optimal Omega-3 blood levels lower the risk of dying from all causes by 85% in high risk patients who had suffered a prior heart attack.

Intrigued by the result of this research, scientists wanted to understand if mortality was affected in individuals with no evident heart disease. A group of men aged 64 to 76 years were supplemented with Omega-3 fats (2.4 grams per day) for a period of 3 years. During that time, the participants showed a 47% reduction in risk of dying from any cause compared to a placebo group. Women experienced a 44% lower risk of death in a similar study.

Omega-3 Fats Lower Systemic Inflammation and Balance Omega-6 Ratios

Omega-3 Enriched Foods and Supplements Balance Fat Ratios and Reduce Inflammation

Omega-3 Enriched Foods and Supplements Balance Fat Ratios and Reduce Inflammation

Researchers from the American Heart Association journal Stroke commented on the ground-breaking conclusions of multiple Omega-3 studies, “Evidence from prospective secondary prevention studies suggests that EPA+DHA supplementation ranging from 0.5 to 1.8 g/d (either as fatty fish or supplements) significantly reduces subsequent cardiac and all-cause mortality.” Omega-3 enriched foods and supplements help to improve the critical balance with Omega-6 fats to lower systemic inflammation. This provides the primary risk-reduction mechanism associated with the long-chain fat.

In addition to fatty fish (salmon, snapper, scallops and shrimp), non-meat food sources of Omega-3’s include walnuts, flaxseeds, chia seeds, raw tofu and cooked soybeans. The body does not efficiently process EPA and DHA fats from vegetarian sources, though strong evidence exists that these food sources still provide exceptional health benefits. To be certain you achieve optimal Omega-3 blood saturation levels as referenced in these studies, nutrition experts recommend supplementing with 2.4 grams per day of combined EPA and DHA (read package labels to ensure proper dose). When supplementing, check that the fish oil (krill oil is also an excellent option) is molecularly distilled to avoid contamination.

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DHA Omega-3 Fat Lowers Risk of Cognitive Decline, Alzheimer’s Disease

November 25, 2011
DHA Omega-3 Fat LowerS Stroke Risk by One-Quarter

DHA Omega-3 Fat LowerS Stroke Risk by One-Quarter

Several recently published articles highlight the critical importance of Omega-3 fats from fatty fish consumption and fish oil supplements. Scientists publishing in the journal Stroke demonstrate that the active DHA Omega-3 fat component helps brain cells to better withstand the stress load placed on the aging brain to lower the risk of a life-altering stroke by as much as a quarter.

Researchers from the Rhode Island Hospital`s Alzheimer`s Disease and Memory Disorders Center have found that DHA from supplements alter the critical brain chemistry and structure to prevent cognitive decline and abnormal brain aging. A wealth of scientific evidence is mounting to document the importance of Omega-3 fats to assist metabolic disorders that lead to dementia, stroke and chronic disease.

DHA, Omega-3 Fat Lowers Brain Inflammation to Improve Cognitive Function

DHA Lowers Brain Inflammation to Improve Cognition

DHA Lowers Brain Inflammation to Improve Cognition

Inflammation of the vital nerves and critical structures of the brain is a precursor to stress that can play an important role in the development of a life-altering stroke. Researchers publish the result of their work designed to determine if Omega-3 fatty acids from fish oil, specifically the long-chain DHA component would be sufficient to reduce neural inflammation and lower risk from a stroke.

To conduct the study, mice were broken into three groups. The first group was supplemented with a DHA-enriched diet, the second group consumed a DHA-depleted diet and the final mice were fed a control diet. After a period of three months, scientists found that only the group with the DHA-enriched diet experienced lower levels of neuroinflammation and had 25% less tissue injury following an induced stroke. They also noted that long-term supplementation resulted in a healthy buildup of DHA fat in brain tissue resulting in an enhanced Omega-3 to Omega-6 fatty acid ratio.

Consumption of Omega-3 Fats Protects the Brain to Lower Damage from a Stroke

DHA Fat Helps Maintain Normal Brain Volume to protect Against Alzheimer's Disease

DHA Fat Helps Maintain Normal Brain Volume to protect Against Alzheimer's Disease

Lead author on the study, Dr. Jasna Kriz concluded “This is the first convincing demonstration of the powerful anti-inflammatory effect of DHA Docosahexaenoic acid Essential Omega 3 fatty acid integral to the health of all cell membranes, nerve and brain function. The consumption of omega-3s creates an anti-inflammatory and neuroprotective environment in the brain that mitigates damage following a stroke.”

Additional evidence of the importance of Omega-3 fats from fish consumption or supplementation is provided by researchers from Rhode Island Hospital. A study was designed using 819 senior participants broken into three groups, those with normal cognition, mild cognitive impairment, and Alzheimer`s Disease. 117 individuals were taking fish oil supplements during the three year course of the study. Taking fish oil supplements was associated with less brain shrinkage and improved cognitive function during the study period.

The lead author, Dr. Lori Daiello concludes, “In the imaging analyses for the entire study population, we found a significant positive association between fish oil supplement use and average brain volumes in two critical areas utilized in memory and thinking.” DHA is preferentially conserved for the construction of neural structures and should be an essential part of your regular menu (from fatty fish) or as a molecularly distilled and purified supplement (500 mg to 1 gram per day) to lower stroke risk and prevent cognitive decline.