Archive for the ‘Broccoli’ Category

h1

Broccoli Influences Gene Expression to Halt Cancer Development

September 25, 2012
Crucifers Found in Broccoli Help Prevent Cancer

Crucifers Found in Broccoli Help Prevent Cancer

Broccoli is a super star member of the cruciferous family, well known and documented as an immune boosting food that supports the healthy clearance of aberrant cancer cells before they multiply and develop into detectable tumors. Researchers reporting in the journal Clinical Epigenetics have found that the bioactive compound in broccoli, sulforaphane provides a multi-modal attack against cancer cell development and proliferation through the complex mechanism of epigenetics.

Epigenetics refers to the way that diet, toxins and other environmental contributors can change which genes get activated, or “expressed” within our genetic code to guide the accurate replication essential to cellular metabolism and repair. This can play a powerful role in preventing and promoting many chronic illnesses from cancer to heart disease and other health issues. Consuming broccoli raw or lightly steamed several times each week can supply a potent dose of sulforaphane to help prevent many types of cancer.

Broccoli and Cruciferous Vegetables Directly Influence Genetic Expression to Inhibit Cancer

Broccoli Influences our DNA to Prevent Deadly Mutations

Broccoli Influences our DNA to Prevent Deadly Mutations

In past research bodies, scientists have documented the pathway utilized by sulforaphane to inhibit the action of an enzyme known as histone deacetylase (HDAC inhibitor) that helps restore proper balance and helps prevent the development of cancer. Researchers at the Linus Pauling Institute at Oregon State University have uncovered a second mechanism, DNA methylation that works in concert with HDAC inhibitors that work to maintain proper cell function. Sulforaphane from broccoli and other crucifers stimulates both HDAC and DNA methylation pathways in a synergistic fashion to prevent cancer development.

The lead study author, Dr. Emily Ho commented regarding the sulforaphane-cancer connection “Cancer is very complex and it’s usually not just one thing that has gone wrong… it’s increasingly clear that sulforaphane is a real multi-tasker. The more we find out about it, the more benefits it appears to have.”

Nutritionists Recommend Three to Five Servings of Broccoli Every Week

Eat Broccoli Several Times Each Week to Benefit

Eat Broccoli Several Times Each Week to Benefit

DNA methylation controls the healthy expression of genes. When this pathway is blocked scientists have found a significantly increased risk of conditions including cardiovascular disease, immune function, neurodegenerative disease and even aging. Foods that provide sulfur groups necessary for proper DNA methylation include onions, garlic, nuts and seeds. Sulforaphane from broccoli is found in this research to stimulate the methylation path to enable normal gene expression to thwart cancer cell genesis.

Nutrition experts recommend consuming one to two servings of broccoli (or other members of the crucifer family such as cabbage, cauliflower, Brussels sprouts or kale) several days of the week. A rapidly growing body of evidence demonstrates that the natural, active compounds found in these vegetables help to prevent cancer and other chronic disease by dealing a two-step knockout blow to influence gene expression.

Advertisements
h1

Broccoli and Crucifer Family Help Lower Colon Cancer Risk

December 21, 2011
Researchers Find Fruits and Vegetables Lower Colon Cancer Risk

Researchers Find Fruits and Vegetables Lower Colon Cancer Risk

Health-minded individuals are well aware that a diet high in natural fruits and vegetables equate to vibrant health and dramatically lowered risk of many chronic diseases. The result of a new study published in the Journal of the American Dietetic Association provides details on how specific fruit and vegetable consumption lowers the incidence of many types of colon cancer, the third most prevalent form of the disease.

Foods such as apples, broccoli and cauliflower each lower the risk of cancer initiation in different parts of the colon while high sugar, fiber-void fruit juices are shown to increase risk of the illness. Nutrition scientists from Australia provide important documentation to confirm the importance of eating a colorful selection of fruits and vegetables to lower colon cancer risk.

Diet Packed With Vegetables and Fruits Shown to Lower Multiple Colon Cancer Risk Factors

Different Vegetable Families Lower Individual Colon Cancer Risk

Different Vegetable Families Lower Individual Colon Cancer Risk

Nutrition researchers have designed studies to examine the effect of healthy diet on colon cancer risk in the past, but the protective effect has been debatable as they do not provide specific results for different foods on the key regions or subsites of the colon. Professor Lin Fritschi, PhD, head of the Epidemiology Group at the Western Australian Institute for Medical Research and her research team set out to investigate the link between fruit and vegetables and three cancers in different parts of the bowel: proximal colon cancer, distal colon cancer and rectal cancer.

The controlled study included 918 participants with a confirmed colon cancer diagnosis and compared them with 1021 individuals with no history of the digestive disease. All participants completed extensive nutritional and demographic questionnaires to account for potential conflicts such as socioeconomic status. Analysis of the data showed that specific fruit and vegetables from similar varietal families affect risk for colon cancer in different portions of the digestive tract.

Broccoli, Cabbage and Sprouts Lower Most Common Type of Colon Cancer

Broccoli and Brassica Vegetables Lower Risk of Most Common Type of Colon Cancer

Broccoli and Brassica Vegetables Lower Risk of Most Common Type of Colon Cancer

With respect to different fruit and vegetable consumption, the researchers found a reduced rate of proximal colon cancer was linked to eating brassicas like broccoli, cabbage, cauliflower and Brussels sprouts. In addition, both total vegetable intake and total vegetable and fruit intake were linked to a lower risk of distal colon cancer. And finally a significant reduction in distal colon cancer risk was linked to dark yellow vegetables and apples.

There should be no doubt that natural fruits and vegetables consumed raw or minimally cooked to retain the active enzymes is a critical factor in digestive health to dramatically lower the risk of colon cancer and other chronic conditions as well. This study conveys the important nature of eating a wide variety of different colored fruits and vegetables, high in phytonutrient content to provide a protective shield at different colon subsites and throughout the body.

h1

Broccoli and Crucifers Selectively Target Cancer Cells

September 6, 2011
Compound in Broccoli and Cauliflower Targets Cancer Cells

Compound in Broccoli and Cauliflower Targets Cancer Cells

Research details published in the Molecular Nutrition & Food Researchjournal explains the potent mechanism exhibited by cruciferous vegetables such as broccoli and cauliflower to ameliorate developing cancer cells. The active photochemical known as

targets prostate and other hormone dependent cancer lines and leaves normal healthy cells unaffected.

Cruciferous vegetables have long been associated with a lowered risk of prostate cancer, but this is the first study to demonstrate the `search and attack` capability of the natural chemical compound. Consuming small amounts of crucifers several times each week can help to significantly lower your risk of developing many types of potentially deadly cancer lines.

Sulforaphane from Broccoli and Crucifers Targets Cancer Cells for Destruction

Sulforaphane from Crucifers Provides a Potent Anti-Cancer Shield

Sulforaphane from Crucifers Provides a Potent Anti-Cancer Shield

The study was led by Dr. Emily Ho, associate professor from the Linus Pauling Institute at Oregon State University. Tissue from cruciferous vegetables such as broccoli, cabbage and cauliflower contain high levels of the powerful natural compound chemically known as glucosinolates. In the body glucosinolates are broken down into sulforaphane that exert protective anti-cancer characteristics.

Based on prior research to indicate that crucifers and sulforaphane specifically kill cancer cells, researchers designed a trial study using mouse models to demonstrate that sulforaphane selectively targets hormone dependent cancers such as breast and prostate. Dr. Ho commented “It is well documented that sulforaphane can target cancer cells through multiple chemopreventive mechanisms” and  continued “Here we show for the first time that sulforaphane selectively targets benign hyperplasia cells and cancerous prostate cells while leaving the normal prostate cells unaffected.”

Natural Food Inhibits Enzymes Necessary for Cancer Development

Broccoli Inhibits an Enzyme Necessary for Cancer Development

Broccoli Inhibits an Enzyme Necessary for Cancer Development

The study demonstrated that sulforaphane is an inhibitor of histone deacetylase, or HDAC enzymes. HDAC enzymes are theorized to develop in the body as a result of metabolic inefficiency resulting from systemic inflammation and low antioxidant status. HDAC enzymes provide fuel to the cancer initiation and progression processes when they occur in excess and their action runs unabated. HDAC inhibition is currently an important research area targeted by Big Pharma and synthesized drugs that can be addressed with natural nutrients from food and lifestyle modifications.

Scientists clearly demonstrated the specific mechanism to explain how sulforaphane targets breast and prostate cancer cells. Many existing studies show that nutrients present in cruciferous vegetables can halt all cancer cell lines by inhibiting the fuel necessary for the cells to multiply out of control. Researchers concluded the data collected “provide(s) further support for the relevance of sulforaphane as a dietary HDAC inhibitor and chemopreventive agent.” Nutritional experts recommend several three to four ounce servings of lightly steamed crucifers each week to prevent cancer development.