Dietary PQQ Supports Brain Health, Boosts Mitochondrial EnergyMay 26, 2011
Nearly 95% of the energy required to fuel our daily activities is provided by the tiny cellular powerhouse structures known as mitochondria. By the time we reach the age of 70, more than half of these critical energy-producing bodies have become damaged or are dysfunctional.
Researchers now understand that the rate of mitochondrial decay is directly related to our length of life. Information presented in The Journal of Biological Chemistry provides startling evidence that a natural compound called pyrroloquinoline quinone (PQQ) can protect mitochondria from free radical damage and stimulate the growth of fresh mitochondria.
PQQ From Diet Prevents Mitochondrial Decay
PQQ is ubiquitous and exists in virtually every plant species tested. Most natural foods supply the nutrient in varying concentrations, though the human body is not capable of synthesizing the compound. It is therefore considered an essential micronutrient and studies published in The FASEB Journal show that PQQ must be supplied through diet to avoid the energy draining effects of mitochondrial decay. Some experts believe that PQQ may have played a pivotal role in the development of life on Earth.
A diet deficient in PQQ can lead to stunted growth, compromised immunity, impaired reproductive capability and fewer numbers of mitochondria in critical organs including the liver, heart and brain. Foods that have been processed or refined are void of PQQ that leads to lower energy levels and ultimately to chronic illnesses such as diabetes, cardiovascular disease and dementia.
PQQ works at the cellular and genetic level to provide protection against mitochondrial damage and to promote the synthesis of new mitochondria structures. Organs with a high energy demand are the most vulnerable to loss of functional ability. The heart, brain and liver are among the most metabolically active and critical organs in the human body, and benefit most from the protective nature provided by PQQ.
PQQ Supports Brain Health, Prevents Cognitive Decline
The Journal of Clinical Biochemistry and Nutrition provides research that highlights the importance of PQQ to the health and proper function of the entire central nervous system. The compound has been shown to reverse the cognitive impairment caused by chronic oxidative stress on delicate neurons, and can improve performance on standardized memory tests. As this stress is believed to be a precursor to the development of Parkinson`s and Alzheimer`s disease, nutritional researchers believe the nutrient may be a key component in the prevention of these devastating conditions.
PQQ has demonstrated efficacy as a cardio-protective agent as it provides a powerful shield against free radicals that damage the heart muscle and mitochondrial DNA after a heart attack. Studies have shown that PQQ is more effective than health-damaging pharmaceuticals typically prescribed after a cardiac event. The compound boosted the energy producing capacity of the organ by protecting against acute oxidative stress.
Many scientific researchers now believe that mitochondrial dysfunction and the loss of cellular energy are linked to the development and progression of virtually all killer diseases of aging. The combination of CoQ10 to maintain mitochondrial function and PQQ to stimulate the development of new mitochondria is a natural way to preserve energy as we age. Experts advise an intake of 20 mg per day of PQQ, the amount available from 8 to 10 servings of fresh vegetables (spinach, green pepper, parsley, tomato) to optimize energy production and lower risk from chronic disease of aging.